Most of the time I use my Spdif in/out for my guitar and it works great. I use my USB when Iwant to use the Line6 software interface. Here is my problem, I have limited ins on my soundcard(m-audio 192) I want to have three inputs(drums,bass and GTR) So I thought, Drums(TD-20's)in with midi and Spdif Bass,analog in and GTR,USB in. When I pull up "audio preference"(soundcard routing)USB(not thru soundcard) is not listed due to it being a direct in(on board soundcard disabled). Just throwing some ideals around and wondering if there are any work arounds. Bardo